Anti-microbial surfaces by plasma assisted immobilization of chitosan.
This report presents the methods and processes involved in the development of an anti-microbial coating of quaternized chitosan on a glass surface. The antimicrobial effect of the quaternized chitosan was tested against a variety of bacteria such as Escherichia coli, Staphylococcus aureus and Pse...
Saved in:
| 主要作者: | |
|---|---|
| 其他作者: | |
| 格式: | Final Year Project |
| 語言: | English |
| 出版: |
2010
|
| 主題: | |
| 在線閱讀: | http://hdl.handle.net/10356/39565 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|
| 機構: | Nanyang Technological University |
| 語言: | English |
| 總結: | This report presents the methods and processes involved in the development of an
anti-microbial coating of quaternized chitosan on a glass surface. The antimicrobial effect
of the quaternized chitosan was tested against a variety of bacteria such as Escherichia
coli, Staphylococcus aureus and Pseudomonas aeruginosa as well as fungi such as
Candida albicans and Fusarium solani to verify its anti-microbial property against
micro-organisms. The anti-microbial coating was applied by two step plasma treatment
(TSPT) using Argon plasma to immobilize quaternized chitosan on the glass surface. The
anti-microbial property of the coating was tested against bacterial Escherichia coli and
the results showed that the quaternized chitosan immobilized surface was capable of
killing the bacteria. Using design of experiments technique, the effects of power and time
duration of each of the 2 steps of the plasma treatment process was investigated. It was
determined that power used in the second step and time duration of the first step was
significant. In addition, there was a significant interaction between the power used in the
first step and time duration of the second step. The plasma treated surface was also
examined by contact angle measurement and the surface characterized using atomic force
microscopy. |
|---|