Analysis of hepatocyte antigen presentation and T cell/hepatocyte interaction in the context of hepatitis B virus Infection.

• Main Author: Noviani, Maria.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Immunology; DRNTU::Science::Biological sciences::Microbiology::Virology
• Online Access: http://hdl.handle.net/10356/39656
• Institution: Nanyang Technological University

Hepatitis B Virus (HBV) has evolved multiple immune escape strategies in order to establish persistent infection in the host. This study aimed to analyze strategies employed by HBV to evade host’s cellular immune response, which requires an interaction of T cell receptor (TCR) and major histocompati...