Expression, purification and characterization of the small hydrophobic (SH) protein of human respiratory syncytial virus (hRSV) : the role of his 22 and his 51 on stabilization of hRSV SH proteins in detergents.

• Main Author: Zhou, Yichao.
• Other Authors: Jaume Torres
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology
• Online Access: http://hdl.handle.net/10356/39782
• Institution: Nanyang Technological University

SH protein of hRSV is a small hydrophobic membrane glycoprotein containing a single-transmembrane domain. Each SH protein contains two protonatable histidine residues: His22 near the N terminal in transmembrane domain and His51 in the C terminal outside transmembrane domain. Previous studies showed...