N-heterocyclic carbene-catalyzed intramolecular stetter reaction between an aldehyde and activated alkyne for easy access to chromones.

• المؤلف الرئيسي: Wong, Qian Ling.
• مؤلفون آخرون: Liu Xuewei
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2010
• الموضوعات: DRNTU::Science::Chemistry::Organic chemistry::Heterocyclic compounds
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/39818
• المؤسسة: Nanyang Technological University

A mild and efficient method for an intramolecular carbon-carbon bond formation between sp2 carbon (aldehyde) and sp carbon (activated alkyne) has been developed using N-Heterocyclic carbene catalyst. This method allows the usage of salicylaldehyde derivatives to assemble a wide pool of chromone deri...