N-heterocyclic carbene-catalyzed intramolecular stetter reaction between an aldehyde and activated alkyne for easy access to chromones.

• 主要作者: Wong, Qian Ling.
• 其他作者: Liu Xuewei
• 格式: Final Year Project
• 語言: English
• 出版: 2010
• 主題: DRNTU::Science::Chemistry::Organic chemistry::Heterocyclic compounds
• 在線閱讀: http://hdl.handle.net/10356/39818

A mild and efficient method for an intramolecular carbon-carbon bond formation between sp2 carbon (aldehyde) and sp carbon (activated alkyne) has been developed using N-Heterocyclic carbene catalyst. This method allows the usage of salicylaldehyde derivatives to assemble a wide pool of chromone deri...