Lentiviral construction to deliver tgf-β3 and knock down type I collagen expression for cartilage therapy.

• Main Author: Citra, Fudiman.
• Other Authors: Wang Dongan
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/39977
• Institution: Nanyang Technological University

Articular cartilage is avascular, and thus, when damaged, will not be able to heal itself. First-line treatment commonly used for articular cartilage disorder aimed to relieve pain from patient while the full recovery is yet to be achieved. Cell therapy is known to have potentials in replicating the...