Construction and application of adenoviral and lentiviral vectors to deliver transforming growth factor β3 and type I collagen-targeting SHRNA for engineered articular chondrogenesis

Construction and application of adenoviral and lentiviral vectors to deliver transforming growth factor β3 and type I collagen-targeting SHRNA for engineered articular chondrogenesis

In this dissertation, we aim to induce type I collagen (Col I)-suppressed chondrogenesis in synovium-derived mesenchymal stem cells (SMSCs) or chondrocytes within 3-dimensional (3D) alginate hydrogel system with the use of adenoviral and/or lentiviral vectors to deliver both transforming growth fact...

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Bibliographic Details
Main Author: Zhang, Feng
Other Authors: Wang Dongan
Format: Theses and Dissertations
Language:English
Published: 2011
Subjects:
DRNTU::Science::Biological sciences::Microbiology::Virology
DRNTU::Science::Medicine::Tissue engineering
Online Access:https://hdl.handle.net/10356/44620
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/44620

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