Mutagenesis and characterization studies of E. Coli DNA-binding protein from starved cells (DPS)

Ferritins are proteins that form spherical protein cages surrounding nanacavities filled with iron.E.coli DNA-binding protein from starved cell (DPS), a mini-ferritin capable of self-assembling into 12-meric (twelve monomers) nanocages, was chosen as the basis for an alanine-shaving mutagenesis stud...

Full description

Saved in:
Bibliographic Details
Main Author: Ang, Emmiline Xiao Wei
Other Authors: Brendan Patrick Orner
Format: Final Year Project
Language:English
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10356/40952
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
Description
Summary:Ferritins are proteins that form spherical protein cages surrounding nanacavities filled with iron.E.coli DNA-binding protein from starved cell (DPS), a mini-ferritin capable of self-assembling into 12-meric (twelve monomers) nanocages, was chosen as the basis for an alanine-shaving mutagenesis study to investigate the importance of key amino acid in controlling protein stability and self-assembly.