Syntheses of bifunctionalized phosphine complexes via ruthenium promoted stepwise hydrophosphination, insertion, hydration, and hydroamination reactions

• Main Author: Luo, Ding
• Other Authors: Leung Pak Hing
• Format: Theses and Dissertations
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds
• Online Access: https://hdl.handle.net/10356/41625
• Institution: Nanyang Technological University

This thesis describes the asymmetric syntheses of bifunctionalized phosphine complexes, which contain a stereogenic center at phosphorus, through various reactions, including insertion, hydrophosphination, hydration, and hydroamination. Promoted by the coordination of diprop-1-ynylphenylphosphine to ruthenium, the two alkyne moieties thereafter were functionalized by different reactions, which thus led to the formation of a chiral phosphorous center. This strategy presented is valuable and can be widely used in the synthesis of chiral phosphines.