An optimal dose-finding technique based on bayesian decision theory for oncology phase I/II clinical trials
A phase I dose-finding clinical trial has always been a challenge to find a safe dosage, given a very limited sample size and shorter timeframe. This is particularly important for cancer trials as new experimental drugs could be cytotoxic and life threatening if too high a dose is given or an inaccu...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2010
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| Online Access: | https://hdl.handle.net/10356/41746 |
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| Institution: | Nanyang Technological University |
| Language: | English |