Investigating the interaction between integrin αL cytoplasmic domain and CD45 full-length cytoplasmic domain.

• المؤلف الرئيسي: Quek, Ardy Rui Ming.
• مؤلفون آخرون: Tan Suet Mien
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2010
• الموضوعات: DRNTU::Science::Biological sciences::Microbiology::Immunology
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/41827
• المؤسسة: Nanyang Technological University

The cell adhesion molecule integrin αLβ2 and the phosphatase CD45 are important molecules in maintaining a functional immune system. Both molecules are transmembrane proteins. CD45 has a large cytoplasmic domain that comprises two subdomains known as D1 and D2. Integrin αLβ2 has two short cytoplasmi...