NMR structure, dynamics and interactions of the integrin β2 cytoplasmic tail with filamin domain IgFLNa21

Integrins are transmembrane proteins that mediate cell adhesion and migration. Each integrin is a heterodimer formed by an α and a β subunit. A large number of cytoplasmic proteins interact with the cytoplasmic tails (CTs) of integrins. The actin-binding cytoskeletal protein filamin A is a negative...

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Bibliographic Details
Main Authors: Chatterjee, Deepak, Tan, Suet-Mien, Bhattacharjya, Surajit, Lu, Lewis Zhiping
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87392
http://hdl.handle.net/10220/45389
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Institution: Nanyang Technological University
Language: English