NMR structure, dynamics and interactions of the integrin β2 cytoplasmic tail with filamin domain IgFLNa21

• Main Authors: Chatterjee, Deepak, Tan, Suet-Mien, Bhattacharjya, Surajit, Lu, Lewis Zhiping
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Integrin; Nuclear Magnetic Resonance (NMR)
• Online Access: https://hdl.handle.net/10356/87392; http://hdl.handle.net/10220/45389
• Institution: Nanyang Technological University

Integrins are transmembrane proteins that mediate cell adhesion and migration. Each integrin is a heterodimer formed by an α and a β subunit. A large number of cytoplasmic proteins interact with the cytoplasmic tails (CTs) of integrins. The actin-binding cytoskeletal protein filamin A is a negative...