Isolation of tubulysins from myxobacteria.

• المؤلف الرئيسي: Lee, Sean Mun Kit.
• مؤلفون آخرون: Liu Chuan Fa
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2010
• الموضوعات: DRNTU::Science::Biological sciences::Microbiology::Bacteria
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/41829
• المؤسسة: Nanyang Technological University

Myxobacteria are prokaryotes found commonly in soil that produces fruiting bodies and a diverse array of secondary metabolites. Tubulysins are highly potent anticancer compounds that are produced by most myxobacteria. Tubulysins disrupt microtubule networks of cancer cells leading to their inability...