Differentiate the roles of CA channel subtypes in insulin secretion

• Main Author: Chen, Peng.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Research Report
• Language: English
• Published: 2010
• Subjects: DRNTU::Engineering::Chemical engineering::Biotechnology; DRNTU::Science::Biological sciences::Human anatomy and physiology::Endocrinology
• Online Access: http://hdl.handle.net/10356/42257
• Institution: Nanyang Technological University

Calcium ion entry through VSCCs is a key step in the coupling of β-cell depolarization with insulin secretion. VSCCs have been described in cell preparations obtained from various species and their biophysical and pharmacological properties have been characterized. Most cells have been shown to e...