Modulation of sphingolipids, cholesterol and saturated fatty acids interact with the neurodegeneration in the Drosophila blue cheese mutant.
The accumulation of insoluble ubiquitinated protein aggregates characterizes many neurodegenerative diseases such as Alzheimer’s disease. Some of these diseases are associated with perturbation of sphingolipids and cholesterol homeostasis. To elucidate the association between aberrant metabolism of...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2011
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| Online Access: | http://hdl.handle.net/10356/42793 |
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| Institution: | Nanyang Technological University |
| Language: | English |