Modulation of sphingolipids, cholesterol and saturated fatty acids interact with the neurodegeneration in the Drosophila blue cheese mutant.

• المؤلف الرئيسي: Boo, George.
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2011
• الموضوعات: DRNTU::Science
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/42793
• المؤسسة: Nanyang Technological University

The accumulation of insoluble ubiquitinated protein aggregates characterizes many neurodegenerative diseases such as Alzheimer’s disease. Some of these diseases are associated with perturbation of sphingolipids and cholesterol homeostasis. To elucidate the association between aberrant metabolism of...