Identification of progesterone-regulated genes and molecular pathways in breast cancer.

Breast cancer is the most common female cancer world-wide and it is the leading cause of death of women aged 45 - 55 in the United States. Two thirds of all breast cancer cases are hormone-dependent and estrogen and progesterone are the primary hormones regulating the development of breast cancer. I...

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Main Author: Lin, Valerie.
Other Authors: School of Biological Sciences
Format: Research Report
Language:English
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/10356/42826
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-428262023-02-28T17:58:23Z Identification of progesterone-regulated genes and molecular pathways in breast cancer. Lin, Valerie. School of Biological Sciences DRNTU::Science::Biological sciences::Genetics Breast cancer is the most common female cancer world-wide and it is the leading cause of death of women aged 45 - 55 in the United States. Two thirds of all breast cancer cases are hormone-dependent and estrogen and progesterone are the primary hormones regulating the development of breast cancer. It is established that estrogen stimulates the growth of breast cancer and its effect is mediated by estrogen receptor (ER). Although antiestrogen tamoxifen is currently the front-line endocrine therapy, most breast cancer ultimately progress as they become tamoxifen resistant. ARC 02/04 2011-01-17T01:29:07Z 2011-01-17T01:29:07Z 2008 2008 Research Report http://hdl.handle.net/10356/42826 en 38 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Science::Biological sciences::Genetics
spellingShingle DRNTU::Science::Biological sciences::Genetics
Lin, Valerie.
Identification of progesterone-regulated genes and molecular pathways in breast cancer.
description Breast cancer is the most common female cancer world-wide and it is the leading cause of death of women aged 45 - 55 in the United States. Two thirds of all breast cancer cases are hormone-dependent and estrogen and progesterone are the primary hormones regulating the development of breast cancer. It is established that estrogen stimulates the growth of breast cancer and its effect is mediated by estrogen receptor (ER). Although antiestrogen tamoxifen is currently the front-line endocrine therapy, most breast cancer ultimately progress as they become tamoxifen resistant.
author2 School of Biological Sciences
author_facet School of Biological Sciences
Lin, Valerie.
format Research Report
author Lin, Valerie.
author_sort Lin, Valerie.
title Identification of progesterone-regulated genes and molecular pathways in breast cancer.
title_short Identification of progesterone-regulated genes and molecular pathways in breast cancer.
title_full Identification of progesterone-regulated genes and molecular pathways in breast cancer.
title_fullStr Identification of progesterone-regulated genes and molecular pathways in breast cancer.
title_full_unstemmed Identification of progesterone-regulated genes and molecular pathways in breast cancer.
title_sort identification of progesterone-regulated genes and molecular pathways in breast cancer.
publishDate 2011
url http://hdl.handle.net/10356/42826
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