Submucosal gland ion channels and cystic fibrosis.

• Main Authors: Gong, Xiandi., Lin, Valerie.
• Other Authors: School of Biological Sciences
• Format: Research Report
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/42830
• Institution: Nanyang Technological University

Cystic fibrosis (CF), the most common fatal genetic disease, is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) [20, 22]. Since the CFTR gene was identified in 1989 [23], a lot of research effort has been focused on either replacing the defective gene or rescuin...