Generation of antibodies towards dengue nonstructural protein 5 using phage display.

• Main Author: Koh, Sabrina Rui En.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology
• Online Access: http://hdl.handle.net/10356/44239
• Institution: Nanyang Technological University

Dengue virus (DENV) is the causative agent of dengue infections worldwide, for which no vaccines or antiviral drugs are available at present. The bifunctional nonstructural protein 5 (NS5) is an attractive target for the development of antibodies since it is integral to the replication complex and e...