Functional and structural characterization of the inter-domain linker region of the dengue virus serotype 4 NS5 protein
Dengue (DENV) NS5 is well conserved and contains a 9 amino acid linker that lies between methylase and RNA-dependent RNA polymerase domains. The crystal structure of DENV-3 FL NS5 is the first dengue NS5 to be successfully documented and can be used as a reference for future plans to crystalise the...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2015
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| Online Access: | http://hdl.handle.net/10356/63146 |
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| Institution: | Nanyang Technological University |
| Language: | English |