Systematic analysis of prenylation of bacterial proteins by eukaryotic host cells through combination of computational protein sequence analysis with wet-lab experimental verifications.
A C-terminal motif on proteins allows for recognition by at least one of three prenyltransferases for addition of an isoprenyl anchor. This post-translational lipid modification, known as prenylation, facilitates membrane localization and protein-protein interaction. The prenylation enzymes are only...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2011
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| Online Access: | http://hdl.handle.net/10356/44505 |
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| Institution: | Nanyang Technological University |
| Language: | English |