Systematic analysis of prenylation of bacterial proteins by eukaryotic host cells through combination of computational protein sequence analysis with wet-lab experimental verifications.

A C-terminal motif on proteins allows for recognition by at least one of three prenyltransferases for addition of an isoprenyl anchor. This post-translational lipid modification, known as prenylation, facilitates membrane localization and protein-protein interaction. The prenylation enzymes are only...

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Bibliographic Details
Main Author: Chan, Siang Yin.
Other Authors: School of Biological Sciences
Format: Final Year Project
Language:English
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/10356/44505
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Institution: Nanyang Technological University
Language: English

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