Exploring the kinetics of the interactions controlling the gating of the Ca2+-release activated Ca2+ channel
Calcium- release activated calcium channels (ORAI) are essential for sustained cytosol [Ca2+] elevation which is required for T cell activation and adaptive immunity. Upon ER luminal Ca2+ depletion, ER Ca2+ sensor STIM1 aggregates and translocates to the ER-PM junction, where it binds and activates...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Final Year Project |
| Language: | English |
| Published: |
2011
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/44746 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Nanyang Technological University |
| Language: | English |