Reengineering cell-surface glycans for anti-cancer applications.

• Main Author: Loo, Janice Xin Yi.
• Other Authors: Liu Chuan Fa
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Biochemistry
• Online Access: http://hdl.handle.net/10356/44747
• Institution: Nanyang Technological University

The expressions of sialic acids are found to be elevated in cancer cells. Research on such expression is of great interest as these glycoconjugates are potential cancer biomarkers. Scientists have developed various chemical techniques like the Staudinger ligation and cycloaddition reaction to label...