Functional role of APP in mediating adult neurogenesis

• Main Author: Joshva Sundara Raj Jasmine Celina
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/44752
• Institution: Nanyang Technological University

Amyloid Precursor Protein (APP) signaling pathway was shown to be negatively implicated in embryonic neurogenesis. Hence in this study, the role APP in mediating adult neurogenesis was investigated in vivo using APP wildtype (WT) and knockout (KO) adult mice at the two neurogenic micrcoenvironments-...