Impaired neurogenesis in the hippocampus of an adult VPS35 mutant mouse model of Parkinson's disease through interaction with APP

Vacuolar protein sorting protein 35 (VPS35) is a core component of the retromer complex involved in regulating protein trafficking and retrieval. Recently, a missense mutation, Asp620Asn (D620N), in VPS35 (PARK17) has been identified as a pathogenic mutation for late-onset autosomal dominant Parkins...

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Main Authors: Jiang, Mei, Tu, Hai-Tao, Zhang, Ke, Zhang, Wei, Yu, Wei-Ping, Xu, Jie, Tan, Eng-King, Guo, Kai-Hua, Zeng, Li
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2022
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Online Access:https://hdl.handle.net/10356/160635
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Institution: Nanyang Technological University
Language: English