Validating a new plasma cell labeling technique for targeted fluorescence in situ hybridization assay in patients diagnosed with multiple myeloma.

• Main Author: Choo, Natasha Swee Lian.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/44856
• Institution: Nanyang Technological University

Fluorescence in situ hybridization (FISH) is a useful tool in diagnosing multiple myeloma (MM), a disease involving abnormal clones of plasma cells. In a standard FISH procedure, all types of cells within the sample are analyzed and scored. A new method, cytoplasmic immunoglobulin (cIg) FISH, has re...