Functional analysis of AP-2γ as an estrogen receptor α (ERα) cofactor in breast cancer.

• Main Author: Png, Jasmine Jie Min.
• Other Authors: Edwin Chong Wing Cheung
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Biochemistry
• Online Access: http://hdl.handle.net/10356/45111
• Institution: Nanyang Technological University

To functionally analyze the role of AP-2γ as an ERα cofactor in breast cancer, we focused on examining the phenotypic role of AP-2γ in breast cancer and question if AP-2γ is able to reprogram the transcriptional network of ERα. From our knockdown experiments in MCF-7, we had demonstrated...