How does a protein fold? A time series segmentation study

• Main Author: Hadidjojo, Jeremy
• Other Authors: Cheong Siew Ann
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Biophysics; DRNTU::Science::Chemistry::Analytical chemistry::Proteins
• Online Access: http://hdl.handle.net/10356/45488
• Institution: Nanyang Technological University

In this work, we perform time series segmentation on average velocity time series of penta-alanine protein simulated in water. We then cluster the segments according to their fluctuation characteristics and discover periods of weak overall fluctuations surrounded by well-aligned segment boundaries....