Rac inactivation decreases cell adhesion strength in chronic myeloid leukaemia
Chronic myeloid leukemia is a hematological malignancy characterized by the reciprocal translocation between chromosomes 9 and 22, resulting in the expression of the constitutively active tyrosine kinase BCR-ABL. The treatment of chronic myeloid leukemia by the tyrosine kinase inhibitior, imatinib,...
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Format: | Final Year Project |
Language: | English |
Published: |
2011
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Online Access: | http://hdl.handle.net/10356/45681 |
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Institution: | Nanyang Technological University |
Language: | English |