Rac inactivation decreases cell adhesion strength in chronic myeloid leukaemia

Chronic myeloid leukemia is a hematological malignancy characterized by the reciprocal translocation between chromosomes 9 and 22, resulting in the expression of the constitutively active tyrosine kinase BCR-ABL. The treatment of chronic myeloid leukemia by the tyrosine kinase inhibitior, imatinib,...

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Bibliographic Details
Main Author: Yang, Joan Xiaohui
Other Authors: Liao Kin
Format: Final Year Project
Language:English
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/10356/45681
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Institution: Nanyang Technological University
Language: English