Studies on the site-specific self cleavage of G-quadruplexes and the topological properties of DNA

• Main Author: Hiew, Shu Hui
• Other Authors: School of Physical and Mathematical Sciences
• Format: Theses and Dissertations
• Language: English
• Published: 2012
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/47844
• Institution: Nanyang Technological University

In this thesis, the studies are classified under two main themes, namely the studies on G-quadruplexes and studies on the topological properties of DNA. Firstly, the effects of several factors that could affect the self-cleaving reactions of G-quadruplex were examined in this study. The opti...