The study of G-quadruplex in supercoiled DNA

It is demonstrated that DNA gyrase, an essential bacterial enzyme which possesses a unique ability to introduce negative supercoils into DNA, can drive G-quadruplex generation from plasmid DNA under the intracellular concentrations of cations in prokaryotes. The outcomes of our investigations could...

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Bibliographic Details
Main Author: Lv, Bei
Other Authors: Li Tianhu
Format: Theses and Dissertations
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/68928
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Institution: Nanyang Technological University
Language: English