The study of G-quadruplex in supercoiled DNA
It is demonstrated that DNA gyrase, an essential bacterial enzyme which possesses a unique ability to introduce negative supercoils into DNA, can drive G-quadruplex generation from plasmid DNA under the intracellular concentrations of cations in prokaryotes. The outcomes of our investigations could...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2016
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Online Access: | https://hdl.handle.net/10356/68928 |
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Institution: | Nanyang Technological University |
Language: | English |