Resistance of DNA G-quadruplex against oxidative stress

The existence of guanine quadruplex (GQ) in the genomic regions with biological significance is closely related to the inhibition of disease progression. Studies have found that GQs at the telomere overhang can inhibit the activity of overly expressed telomerase in the cancer cells. Furthermore, the...

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Bibliographic Details
Main Author: Wee, Xue Xin
Other Authors: Shao Fangwei
Format: Theses and Dissertations
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/50941
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Institution: Nanyang Technological University
Language: English