Resistance of DNA G-quadruplex against oxidative stress
The existence of guanine quadruplex (GQ) in the genomic regions with biological significance is closely related to the inhibition of disease progression. Studies have found that GQs at the telomere overhang can inhibit the activity of overly expressed telomerase in the cancer cells. Furthermore, the...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2012
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Online Access: | https://hdl.handle.net/10356/50941 |
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Institution: | Nanyang Technological University |
Language: | English |