Structural diversity of G-rich DNA : from telomeric G-quadruplexes to G-junction motifs

• المؤلف الرئيسي: Lim, Kah Wai
• مؤلفون آخرون: Phan Anh Tuan
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Biological sciences::Biochemistry; DRNTU::Science::Biological sciences::Biophysics; DRNTU::Science::Chemistry::Analytical chemistry::Nucleic acids; DRNTU::Science::Chemistry::Biochemistry::Spectroscopy
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/55392
• المؤسسة: Nanyang Technological University

Four-stranded G-quadruplex DNA have been implicated in cellular processes and shown to exhibit important functional properties. In particular, putative quadruplex motifs were identified in important genomic loci including telomeres and oncogenic promoters, rendering them promising therapeutic target...