Structural diversity of G-rich DNA : from telomeric G-quadruplexes to G-junction motifs

• 主要作者: Lim, Kah Wai
• 其他作者: Phan Anh Tuan
• 格式: Theses and Dissertations
• 語言: English
• 出版: 2014
• 主題: DRNTU::Science::Biological sciences::Biochemistry; DRNTU::Science::Biological sciences::Biophysics; DRNTU::Science::Chemistry::Analytical chemistry::Nucleic acids; DRNTU::Science::Chemistry::Biochemistry::Spectroscopy
• 在線閱讀: https://hdl.handle.net/10356/55392

Four-stranded G-quadruplex DNA have been implicated in cellular processes and shown to exhibit important functional properties. In particular, putative quadruplex motifs were identified in important genomic loci including telomeres and oncogenic promoters, rendering them promising therapeutic target...