Genome-wide gene expression profiling of the Angelman syndrome mouse with Ube3a mutation : from genotype to phenotype
Angelman syndrome (AS) is an inheritable neurodevelopmental disorder resulting from the loss of function of the ubiquitin E3A ligase (UBE3A). Clinical features of the disorder include severe mental retardation, motor incoordination and perpetual happy disposition. Associated features of AS include h...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2012
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| Online Access: | https://hdl.handle.net/10356/48088 |
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| Institution: | Nanyang Technological University |
| Language: | English |