Proteomics analysis of an UBE3A knockout mouse modelling Angelman syndrome
Angelman syndrome is a neurobehavioral disease associated with the loss of maternally expressed E3 ubiquitin protein ligase, Ube3a. Ube3a gene is biallelically expressed in all tissue except cerebellum, Purkinje cells and hippocampus, in which Ube3a is expressed exclusively from maternally inherited...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2014
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| Online Access: | https://hdl.handle.net/10356/55407 |
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| Institution: | Nanyang Technological University |
| Language: | English |