Rho GTPases and regulation of cell migration, polarization and adhesion proteins in wounding assay of human corneal epithelial cells

• Main Author: Gan, Kah Hui
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/49345
• Institution: Nanyang Technological University

Corneal epithelial cells are involved in ocular surface diseases involving defective wound healing or persistent epithelial erosions. The small G proteins subfamily of the Ras superfamily is known to play a role in cell motility, polarization and modulation of adhesion proteins. Here we show that va...