Using fluorescent timer to study protein inclusion biogenesis and removal by autophagy.
Protein inclusion, formed from the aggregation of misfolded proteins can be degraded by autophagy. Autophagy has been shown to be a selective process dependent on the nature of the protein inclusions. Research on whether and how the aggregation pattern of an aggregate-prone protein influences its ha...
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Format: | Final Year Project |
Language: | English |
Published: |
2012
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Online Access: | http://hdl.handle.net/10356/49399 |
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Institution: | Nanyang Technological University |
Language: | English |