Using fluorescent timer to study protein inclusion biogenesis and removal by autophagy.

• Main Author: Lee, Pei Yu.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2012
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/49399
• Institution: Nanyang Technological University

Protein inclusion, formed from the aggregation of misfolded proteins can be degraded by autophagy. Autophagy has been shown to be a selective process dependent on the nature of the protein inclusions. Research on whether and how the aggregation pattern of an aggregate-prone protein influences its ha...