Characterisation of sox6 function in zebrafish using mutant alleles generated by Zinc Finger Nuclease (ZFN)-mediated targeted mutagenesis.

• Main Author: Kong, Hui Yi.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2012
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/49908
• Institution: Nanyang Technological University

Sox6 is a multi-faceted transcription factor that has been implicated in regulating differentiation in many development areas, including chondrogenesis, skeletal muscle differentiation, oligodendrocyte and neuronal differentiation, and erythropoiesis, in the mammalian embryo. In some cases, Sox6 see...