Characterization of zebrafish IKK2 mutants generated by zinc finger nucleases
IκB kinase β (IKK2/IKKβ) is known as a master regulator of NF-κB signaling, which mediates stress, immune and inflammatory responses. Unfortunately, embryonic lethality in IKK2-deficient mice hinders studies of zygotic IKK2 function beyond embryonic stages. Although conditional knockout mice have be...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2014
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| Online Access: | http://hdl.handle.net/10356/59585 |
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| Institution: | Nanyang Technological University |
| Language: | English |