Biophysical and structural studies of self-assembled liposome/E-peptide/DNA nanoparticles : correlation with gene delivery

Recently, novel DNA compaction agents, ε-oligo(L-lysines) and their branched α-amino-acid substituted derivatives, have been successfully tested as vectors for in vitro gene delivery. The present work exploits a number of newly developed ε-oligolysine-based peptides: ε-(LYRH)K10, ε-(LYH)K10, ε-(LYK)...

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Bibliographic Details
Main Author: Yan, Jiang
Other Authors: Lars Nordenskiold
Format: Theses and Dissertations
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/50471
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Institution: Nanyang Technological University
Language: English