Structure and internal organization of overcharged cationic-lipid/peptide/DNA self-assembly complexes

• المؤلفون الرئيسيون: Yan, Jiang, Korolev, Nikolay, Su, Chun-Jen, Nordenskiöld, Lars, Berezhnoy, Nikolay V.
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/98791; http://hdl.handle.net/10220/12747
• المؤسسة: Nanyang Technological University

The combination of cationic lipids with cationic peptides and DNA vectors can produce synergistic effects in gene delivery to eukaryotic cells. Binary complexes of cationic lipids with DNA are well-studied whereas little information is available about the structure of the ternary lipid/peptide/DNA (...