Proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol

Proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol

Currently, drug discovery and development is extremely expensive and time consuming, which results in low rates of new drugs reaching the market. One solution to alleviating this problem is to gain a better understanding of existing drug-cell interactions that will provide valuable insights into dru...

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Main Author: Wang, Mingxuan
Other Authors: Chen Wei Ning, William
Format: Theses and Dissertations
Language:English
Published: 2012
Subjects:
DRNTU::Engineering::Chemical engineering::Biochemical engineering
Online Access:https://hdl.handle.net/10356/50476
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-504762020-11-06T00:06:00Z Proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol Wang, Mingxuan Chen Wei Ning, William Ching Chi Bun School of Chemical and Biomedical Engineering DRNTU::Engineering::Chemical engineering::Biochemical engineering Currently, drug discovery and development is extremely expensive and time consuming, which results in low rates of new drugs reaching the market. One solution to alleviating this problem is to gain a better understanding of existing drug-cell interactions that will provide valuable insights into drug redeployment and new drug design. Protein and metabolite concentrations represent sensitive markers of cellular responses to drug treatment. Consequently, developing robust cell line-based proteomics and metabolomics platforms will greatly facilitate understanding of drug-cell interactions. DOCTOR OF PHILOSOPHY (SCBE) 2012-06-06T02:11:19Z 2012-06-06T02:11:19Z 2012 2012 Thesis Wang, M. X. (2012). Proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/50476 10.32657/10356/50476 en 172 p. application/msword
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Chemical engineering::Biochemical engineering
spellingShingle DRNTU::Engineering::Chemical engineering::Biochemical engineering
Wang, Mingxuan
Proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol
description Currently, drug discovery and development is extremely expensive and time consuming, which results in low rates of new drugs reaching the market. One solution to alleviating this problem is to gain a better understanding of existing drug-cell interactions that will provide valuable insights into drug redeployment and new drug design. Protein and metabolite concentrations represent sensitive markers of cellular responses to drug treatment. Consequently, developing robust cell line-based proteomics and metabolomics platforms will greatly facilitate understanding of drug-cell interactions.
author2 Chen Wei Ning, William
author_facet Chen Wei Ning, William
Wang, Mingxuan
format Theses and Dissertations
author Wang, Mingxuan
author_sort Wang, Mingxuan
title Proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol
title_short Proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol
title_full Proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol
title_fullStr Proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol
title_full_unstemmed Proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol
title_sort proteomics and metabolomics analysis of cellular responses to β-blocker carvedilol
publishDate 2012
url https://hdl.handle.net/10356/50476
_version_ 1688665634356854784

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