Green tea catechin, EGCG, modulates mitochondrial dynamics in dopaminergic neurons of α-synuclein transgenic flies resulting in mobility improvement.

• Main Author: Choo, Wen Rui.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2012
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/50655
• Institution: Nanyang Technological University

Parkinson’s disease (PD) is characterized pathologically by the hallmark presence of Lewy bodies, which are intraneuronal inclusions comprised of chiefly α-synuclein. Studies have illustrated an association between the toxicity induced by over-expression of α-synuclein and PD-related locomotive defi...