Synthesis and application of PLA/PEG block copolymers as anti-cancer drug carriers

This study consists of four main parts: (a) the synthesis and characterization of triblock, diblock and star-shaped PLA/PEG block copolymers; (b) the preparation and characterization of micelle-like nanoparticles (c) the in vitro degradation properties of block copolymer in film and nanoparticle for...

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Bibliographic Details
Main Author: Pan, Jie
Other Authors: Subbu S. Venkatraman
Format: Theses and Dissertations
Published: 2008
Subjects:
Online Access:https://hdl.handle.net/10356/5115
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Institution: Nanyang Technological University
Description
Summary:This study consists of four main parts: (a) the synthesis and characterization of triblock, diblock and star-shaped PLA/PEG block copolymers; (b) the preparation and characterization of micelle-like nanoparticles (c) the in vitro degradation properties of block copolymer in film and nanoparticle forms and (d) the release profiles of 5-FU and paclitaxel from micelle-like nanoparticles.