Synthesis of hydroxyapatite hollow microspheres and their use in gastric retentive drug delivery systems
A totally erodible gastroretentive dosage form made of calcium alginate, sunflower oil and hydroxyapatite (HA) hollow microspheres (HMS) as the radiopacifer was developed. Porous thin-shelled HA HMSs in a ping-pong shape were successfully synthesized in a nozzle-reactor system with a thermosetting p...
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| Format: | Theses and Dissertations |
| Published: |
2008
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| Online Access: | https://hdl.handle.net/10356/5116 |
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| Institution: | Nanyang Technological University |