Synthesis of hydroxyapatite hollow microspheres and their use in gastric retentive drug delivery systems

A totally erodible gastroretentive dosage form made of calcium alginate, sunflower oil and hydroxyapatite (HA) hollow microspheres (HMS) as the radiopacifer was developed. Porous thin-shelled HA HMSs in a ping-pong shape were successfully synthesized in a nozzle-reactor system with a thermosetting p...

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Bibliographic Details
Main Author: Tang, Yongdan
Other Authors: Freddy Boey
Format: Theses and Dissertations
Published: 2008
Subjects:
Online Access:https://hdl.handle.net/10356/5116
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Institution: Nanyang Technological University
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